Iodine Global Network (IGN)

IODINE Global Network

Risk for iodine deficiency and hypothyroidism high in children on parenteral nutrition

Children who are receiving chronic parenteral nutrition (PN) therapy may be at a higher risk of developing an iodine deficiency and subsequent hypothyroidism, according to a study published in Pediatrics.

Researchers performed a cross-sectional study in 27 children at Cincinnati Children's Hospital in Ohio who were younger than 17 years old who have received PN for more than 6 months and who received less than 50% of their total nutrition enterally, to determine the prevalence of iodine deficiency and hypothyroidism.

Study results showed that of the 24 patients with available thyroid function tests, 8 patients had hypothyroidism, defined as thyrotropin (TSH) level >4 µIL/L, 6 had a TSH level >10 µIL/mL, and 4 had severe hypothyroidism with concurrent low free thyroxine levels.